Abstract
Some biochemical gas-sensors (bio-sniffer devices) for smell informatics were developed using biological materials, such as xenobiotic metabolizing enzymes, and a reaction cell with both gas and liquid phase compartments separated by a porous diaphragm membrane. The bio-sniffer devices could be used to measure alcohol, acetaldehyde, formaldehyde, trimethylamine, methyl mercaptan, dimethyl sulfide, hydrogen peroxide in the gas phase with gas selectivity being attributable to substrate specificity of enzymes. Stick-type sniffer devices fabricated by screen-printing and microfabrication techniques were successfully applied for evaluating breath alcohol and acetaldehyde after drinking.
A biochemical nose system was constructed using 4-ch oxygen sensitive optical fiber array with the enzyme immobilized membranes. A smell communication with over 80% of transmissibility was carried out using 4-ch gas generator connected with the nose system
