2021 Volume 12 Issue 1 Pages 30-36
Continuous renal replacement therapy (CRRT) is the mainstay of blood purification therapy in the critical care setting. CRRT machines are used to ensure precision and safety during CRRT. The improvement of CRRT-specific machines started with the refinement of the flow control of each pump. Currently, the machines have evolved to include various safety features. European and American machines are capable of performing pre-dilution continuous hemofiltration (CHF), and are also equipped with innovative air-drip chambers and heating systems, while Japanese machines have not been able to perform pre-diluted CHF. However, the TR-2020 (Toray Medical Inc.) is now available and can perform pre-dilution CHF safely. While CRRT machines might not be able to make progress in the future, improvements can be expected in the development of a mode to reduce power consumption in case of disasters and in downsizing and transportability. If such a machine can be developed, the range of applications of CRRT will expand further.