Journal of Japan Society for Blood Purification in Critical Care
Online ISSN : 2434-219X
Print ISSN : 2185-1085
Comparison of permeability and antithrombotic properties of two Polysulfone (PS) membranes
Comparison of EXCELFLO® AEF-13 and HEMOFEEL® SNV-1.3
Tatsumi YamasakiNene AdachiYuuichi OdaTakeshi YanoMasahiko TaniguchiTetsuro Shirasaka
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2022 Volume 13 Issue 1 Pages 64-68

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Abstract

In recent years, HEMOFEEL® SNV, in which an NV polymer is localized on the inner surface of the hollow fiber of a Polysulfone (PS) membrane hemofilter, has been sold. NV polymers are believed to have improved antithrombotic properties by suppressing protein adhesion (fouling). In order to investigate the permeability and antithrombotic properties of HEMOFEEL® SNV, we compared it with other companies’ PS membrane hemofilters. The subjects were 56 adult patients who underwent CHDF (continuous hemodiafiltration) using PS membrane hemofilters, and the number of membranes was 226. The patients were divided into the EXCELFLO® AEF-13 group and the HEMOFEEL® SNV-1.3 group, and the transmembrane pressure (TMP), ultrafiltration rate (UFR), and lifetime were compared. The results suggested that the HEMOFEEL® SNV-1.3 group had significantly lower TMP and significantly higher UFR, which was advantageous for high flow rate filtration settings.

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© 2022, Japan Society for Blood Purification in Critical Care
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