A case of acute exacerbation of interstitial pneumonia that was effectively treated with early endotoxin adsorption therapy

Abstract

A 70-year-old female patient diagnosed with interstitial pneumonia was kept under observation due to the absence of respiratory symptoms. Five days before admission, she experienced worsening respiratory distress and was admitted to our emergency center with acute exacerbation of interstitial pneumonia. She presented with type Ⅱ respiratory failure and was treated with steroid pulse therapy and polymyxin B-immobilized fiber column under ventilator management for diffuse alveolar damage. After 8 hours of polymyxin B-immobilized fiber column administration, her oxygenation improved to a P/F ratio of 199. She was placed on high-flow nasal oxygen therapy on day 6 and transferred to the Department of Respiratory Medicine on day 8.