2011 Volume 2 Issue 1 Pages 87-91
In the field of emergency and critical care, continuous hemodiafiltration (CHDF) becomes the very important blood purification therapy. However, currently, CHDF conditions including the type of blood purification device vary among hospitals. We established the Yamanashi CHDF Standardization Working Group (WG), and investigated methods to rinse circuits, including blood purification devices, the optimal activated clotting time (ACT) during anti-coagulant therapy, and operational conditions in a survey regarding CHDF conditions in each hospital located in Yamanashi Prefecture. We recommended that blood purification devices and circuits be rinsed in 2,000mL of fluid and 500mL of anti-coagulant-containing solution in reference to the package inserts, and that the target ACT be established as 140 to 200 seconds on the exsanguination side and 180 to 230 seconds on the return side. In addition, the water balance should be regulated with the substitution fluid volume. However, these should be inspected more. It is also possible to standardize other CHDF conditions through discussion. CHDF conditions should be promptly standardized.
