2015 Volume 6 Issue 2 Pages 153-155
Insufficient bilirubin adsorption due to the performance limit of the devices and/or fibrin Precipitation is sometimes experienced. We report a case of post-operative liver failure. The patient underwent plasma bilirubin adsorption therapy using selective membrane plasma separator Evacure EC-4A10 as a primary filter. Bilirubin adsorption was performed 7 times, processing 30L of plasma per procedure. The time course changes of total bilirubin (T-Bil), fibrinogen (Fib), and platelet (Plt) were examined. The mean decreasing-rate of T-Bil after treatment was 53.6% (range: 45.5〜61.4%). The change of serum Fib and Plt were ranged within from −22% to +22% and within from −15% to +31%, respectively. It is suggested that fibrin deposition and hemolysis were prevented effectively by using Evacure EC-4A as a primary filter for plasma adsorption therapy.