AN69ST膜によるCHDF実施時のlifetime延長を目的とした技術的検討

芝田 正道; 小川 哲也; 小林 利道; 今泉 力也; 松本 健一; 森谷 紘旭; 岡本 遼; 廣瀬 沙優里; 豊見山 真智子; 桧垣 洋平; 近藤 敦子; 坂口 祥章; 石井 真佐隆; 鮫島 麻子; 川名 由浩; 庄古 知久

doi:10.34325/jsbpcc.8.1_106

A technological study for the purpose of prolonging lifetime when CHDF is carried out using the AN69ST membrane

Masamichi Shibata, Tetsuya Ogawa, Toshimichi Kobayashi, Rikiya Imaizumi, Kenichi Matsumoto, Hiroaki Moriya, Ryo Okamoto, Sayuri Hirose, Machiko Tomiyama, Atsuko Kondou, Yohei Higaki, Yoshiaki Sakaguchi, Masataka Ishii, Asako Samejima, Yoshihiro Kawana, Tomohisa Shoko

Author information

Masamichi Shibata
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Tetsuya Ogawa
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Depertment of Medicine, Tokyo Women’s Medical University Medical Center East
Toshimichi Kobayashi
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Rikiya Imaizumi
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Kenichi Matsumoto
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Hiroaki Moriya
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Ryo Okamoto
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Sayuri Hirose
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Machiko Tomiyama
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Atsuko Kondou
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Yohei Higaki
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Yoshiaki Sakaguchi
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Masataka Ishii
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Asako Samejima
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Yoshihiro Kawana
Deparment of Crinical Engineering, Tokyo Women’s Medical University Medical Center East
Tomohisa Shoko
Emargency and Critical Care Center, Tokyo Women’s Medical University Medical Center East

Keywords: AN69ST membrane, the priming method using nafamostat mesylate, A/V dispensation method, lifetime

JOURNAL FREE ACCESS

2017 Volume 8 Issue 1 Pages 106-110

DOI https://doi.org/10.34325/jsbpcc.8.1_106

Details

Abstract

The AN69ST membrane for sepsis patients is covered by insurance and it is expected to be effective. On the other hand, it has become a matter of particular concern that the adsorption of nafamostat mesilate by membranes might shorten the lifetime (lifetime of membranes and blood circuits). A reduced lifetime is associated with several problems such as reduced treatment efficiency, increased workload associated with circuit exchanges, and increased economic burden. In this study, we compared the priming method using nafamostat mesylate in pursuit of the effect of prolonging the lifetime of the AN69ST membrane and the method of anticoagulant addition injection (A/V dispensation method) from the side of blood transmission that has been conventionally carried out. A significant extension of lifetime was therefore recognized using the A/V method.

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