2017 Volume 8 Issue 1 Pages 72-75
Hematogenous dissemination of Klebsiella pneumoniae from a liver abscess causes systemic infection due to potent toxicity. We report a case of systemic septic embolism caused by Klebsiella pneumoniae, which originated from a liver abscess in a patient with type 2 diabetes mellitus who recovered following intensive care. A 52-year-old woman with a history of type 2 diabetes mellitus was admitted to hospital because of a high fever and consciousness disorder, and was diagnosed with systemic septic infection (multiple liver abscesses, pulmonary embolisms, meningitis and pyelonephritis). At admission, disseminated intravascular coagulation and multiple organ failure was detected. Blood culture showed heavy growth of Klebsiella pneumoniae. The patient’s general condition steadily improved after antibiotic treatment with polymyxin B hemoperfusion (PMX-DHP) and continuous hemodiafiltration (CHDF) in the intensive care unit. However, growth of a lung cavity lesion caused acute respiratory failure, and artificial respiratory care was required. A percutaneous gastrostomy tube was also placed. The patient’s general condition improved after weaning from positive pressure ventilation. Finally, oral ingestion was possible, and she was transferred to a rehabilitation hospital. Blood purification therapy from an early stage of disease was useful for multiple organ failure.
