A report on renal function and prognosis of patients with septic shock who received CHDF

Abstract

【Background】At emergency units, it is often the case that the patient’s data such as consultation record, medical history, and baseline serum creatinine level and urine volume are unknown at the time of arrival, which can prolong the time necessary to diagnose acute kidney injury (AKI) or chronic kidney disease (CKD). We investigated the renal function and life prognosis of patients with septic shock who were transferred to our center and received CHDF.【Methods】The renal function and life prognosis of 40 patients who were transferred to our center between January 2014 and March 2016 and experienced septic shock at the initiation of CHDF were reviewed retrospectively.【Results】Patient demographics and other characteristics were as follows : age, 70±16 years old ; Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ) score, 31 points ; 28-day survival rate, 85％ ; and standardized survival rate, 3.4. Of the patients with septic shock, 70％ had acute kidney injury (AKI) with a median “Kidney Disease : Improving Global Outcomes (KDIGO)” of 2, and 90％ had renal disorder, including chronic kidney disease (CKD). All patients with AKI who survived, excluding 4％ who switched to maintenance dialysis, were cured of AKI.【Conclusions】Of the patients, 70％ experienced AKI but had a good life prognosis.