Abstract
Recent new technologies for human molecular genetics such as the genome-wide human SNP array, array-compar-ative genomic hybridization, and high-throughput sequencing, revealed that neural cell adhesion molecules widely implicate the pathophysiology of various neuropsychiatric disorders. Neurexins/Neuroligins were especially discov-ered as one of the susceptibility genes for autism, schizophrenia, and addiction. NrCAM was also explored involving in the pathophysiology of addiction. In this review, recent advances in the genetics of neuropsychiatric disorders and our achievement related to the neural cell adhesion molecules were outlined.
