Abstract
Periodic psychosis of puberty is a pathology often found in girls around the onset of menses, and it is characterized by psychological symptoms, such as periodic mood swings, behavioral inhibition, psychotic experiences and a dreamy state. Some studies consider it a mood disorder in preadolescence and classify it as atypical psychosis. However, others argue that it is a symptomatic psychosis of physiologically premature women. It is important to construct biological measures including concepts of trait marker and state marker when evaluating periodic psychosis. Moreover, some electroencephalograms to follow up possible disturbance of consciousness are essential. In this article, I would like to discuss an overview of clinical features, pathological basis, and treatment of periodic psychosis of puberty. I would also like to emphasize the importance of biologoical measures to better understand and evaluate psychosis, especially periodic psychosis.
