Japanese Journal of Biological Psychiatry
Online ISSN : 2186-6465
Print ISSN : 2186-6619
Synergistic effect of SSRI/SNRI and mutual interaction on the development of social affiliation behavior through high sensitive period
Shun Nakamura[in Japanese]
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JOURNAL OPEN ACCESS

2011 Volume 22 Issue 1 Pages 39-43

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Abstract
Social affiliation develops through sensory-motor interaction between social agents. We have established a new integrative behavior analysis method to quantitatively evaluate the social behavior and examined the development of social affiliation behavior in two animal models (domestic chick and common marmoset). We found that chick developed the affiliation behavior through a sensitive period and SSRI/SNRI was effective for the chick which did not experience social interaction in the period, but did after the period. This result suggests the possible contribution of our animal model to shed more light on the neural basis of social behavior deficit in developmental disorders and other psychiatric disorders.
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© 2011 Japanese Society of Biological Psychiatry
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