Abstract
A growing evidence of the stress vulnerability in response to early adversities, maternal care plays an important role in the development of susceptibility to mental disorders. In this article, we would like to show the involvement of early adversi-ty in the development of the stress vulnerability, using neonatal isolation, postpartum depression model, and early lighting condition. In addition, we would like to demonstrate how environmental enrichment after weaning ameliorates the stress vulnerability in response to early adversities.
