Japanese Journal of Biological Psychiatry
Online ISSN : 2186-6465
Print ISSN : 2186-6619
Pharmacological manipulation of fear memory to treat anxiety disorders
Mitsuhiko YamadaKie AkagiMisa YamadaAkiyoshi SaitohJun-Ichiro Oka
Author information
JOURNAL OPEN ACCESS

2018 Volume 29 Issue 2 Pages 60-63

Details
Abstract
Exposure therapy has recently been gaining increasing attention for the treatment of a range of anxiety disorders. Recently, strategies to facilitate extinction of fear memory have attracted increasing attention for enhancing the effectiveness of exposure therapy. There is a strong clinical need for an anxiolytic drug that 1)does have potent anxiolytic effect, 2)does not impair recognition memory, 3)does not impair (or even facilitates) extinction learning and 4)attenuates reconsolidation of fear memory. A drug with these features would enhance exposure therapy without the undesired side effects reported for benzodiazepines, SSRIs and D-cycloserine.
Content from these authors
© 2018 Japanese Society of Biological Psychiatry
Previous article Next article
feedback
Top