Abstract
During the developmental period, immature neurons that proliferate from stem cells begin migration toward their final destinations. Neuronal migration is essential for the construction of neural structures and networks, and recent studies have reported that abnormalities in neuronal migration are associated with neuropsychiatric disorders. Migrating neurons respond to various extracellular factors and accordingly adjust their migratory routes and migration modes. These adaptations are modulated by several intracellular signaling pathways, and among these, the Ca2+ signaling pathway reportedly plays a pivotal role in regulating neuronal migration. In this review, we overview the Ca2+‐dependent signaling pathways that regulate neuronal migration and highlight the dysfunctions of Ca2+ signaling associated with neuropsychiatric disorders.
