Abstract
Although disturbed prefrontal cortex functions are observed in multiple psychiatric disorders, the common cause remains unknown. On the other hand, aversive childhood experiences have been implicated in the pathogenesis of psychiatric disorders such as schizophrenia and neurodevelopmental disorders, and therefore, childhood experiences‐inducing dysfunction of the prefrontal cortex possibly develop psychiatric disorders. In this review article, we discuss the relationship between childhood experiences and the function of prefrontal cortex from the viewpoint of myelination which is produced by oligodendrocytes.
