Japanese Journal of Biological Psychiatry
Online ISSN : 2186-6465
Print ISSN : 2186-6619
Gut Microbiome in Autism Spectrum Disorders
Syunya KurokawaTaishirou KishimotoKenji SanadaMasaru Mimura
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JOURNAL OPEN ACCESS

2019 Volume 30 Issue 2 Pages 55-59

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Abstract
Interest in the microbiota‐gut‐brain axis, in which the intestine and the brain interact with each other via the microbiome and its metabolites, is rapidly growing. Autism spectrum disorder (ASD) is one of the most reported microbiota‐related disorders in the neuropsychiatric field. In ASD, differences in specific bacterial species and/or diversity (dysbiosis) as compared to healthy controls have been previously reported. Fecal Microbiota Transplantation (FMT) , for the purpose of restoring dysbiosis, has been noted as a novel treatment option for ASD. In this paper, we introduce up‐to‐date observational and intervention studies regarding the microbiota‐gut‐brain axis, and discuss future prospects, such as the possibility of therapeutic application and understanding the pathology of ASD through microbiome studies. There are no potential conflicts of interest to disclose.
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© 2019 Japanese Society of Biological Psychiatry
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