Abstract
Lithium, a naturally occurring element, is generally accepted for bipolar disorder and treatment‐resistant depression. Recent researches have indicated that lithium may exert preventive effects of suicide and/or dementia. Furthermore, these effects may work even at concentrations much lower than the clinically therapeutic concentrations. In this review, we showed relevant articles regarding the association of trace lithium with suicide, dementia to assess the present state of trace lithium’s effect on mental state. Further studies are warranted to investigate whether trace lithium is effective for mental health.