Abstract
Technologies for personalized medicine, which enables decision‐making for effective and safe medical practice adjusted for each individual based on genome and other biological information, have been developed and installed in various medical fields, such as cancer medicine. In 2012, the following year of the Great East Japan Earthquake, the Tohoku Medical Megabank Project was founded as a flagship project for rebuilding the medical system in the devastated region and as a core resource to develop a personalized medicine system of the nation. The cohort (consists of 150,000 residents) has investigated health, lifestyle, and environmental information, provided feedback and support to the communities and accumulated genome and other biological information. The project targets a wide range of health problems, including psychiatric conditions such as depression. It is expected that the project contributes to the elucidation of the pathogeneses of neuropsychiatric disorders and the development of personalized psychiatric medicine.
