Abstract
In spite of the rapid progress of science, the diagnosis of psychiatric disorders is still based on a list of symptoms, and there are still no biomarkers that can be clearly visualized as other physical disorders. This is especially true for schizophrenia, which is still a mystery. On the other hand, recent studies have provided consistent evidence that the pathological basis of schizophrenia is related to abnormalities in gamma oscillation, a rhythmic activity with higher frequency of neural oscillation in the brain. The gamma oscillation can be measured relatively easily by electroencephalography (EEG) and magnetoencephalography (MEG) and is one of the best indicators to visualize the ever‐changing brain activity with high temporal resolution. Furthermore, basic research has also elucidated its generation mechanism, making it suitable for translational research. Thus, gamma oscillation is the best candidate as a functional indicator to visualize the varied and abnormal brain and psychotic phenomena in schizophrenia. In this review, we tried to discuss how to visualize the psychotic phenomena of schizophrenia based on gamma oscillation and how to elucidate the pathophysiology of schizophrenia and develop new treatment methods.
