2023 Volume 34 Issue 1 Pages 13-18
Early psychosis, which is a concept that evolved in association with early intervention activities for psychiatric disorders, generally includes first episode psychosis (e. g., schizophrenia) and clinical high‐risk state for developing psychosis (at‐risk mental state : ARMS) . Magnetic resonance imaging studies of early psychosis have suggested that brain morphological features, such as gray matter volume changes, contribute to discriminating schizophrenia patients from healthy controls in the early illness stages and to predicting future psychosis onset in ARMS individuals. Further development of brain imaging studies for early psychosis in multicenter design and combination of brain imaging findings with other biological indices, such as event‐related potentials and blood markers, would lead to clinical application of these findings, while there are still remaining issues to be addressed before transferring these research findings to the clinical setting.
