Abstract
Neuropathological classification of neurodegenerative diseases has been established based on proteinopathy, which indicates neuronal loss and gliosis associated with protein specific inclusions in the focal regions responsible for clinical signs and symptoms. Although the neuropathology of psychiatric disorders, such as schizophrenia and bipolar disorder still remain obscure, the organization of psychiatric Brain bank proceeds accumulation of brain tissue as research resources. The most important role of neuropathology in brain bank is to pronounce correct neuropathological diagnosis, because combination of various proteinopathies, such as Alzheimer’s disease and Parkinson’s disease, cerebrovascular disorders, trauma and ischemic changes in the terminal stages modify the pathological findings. Brain bank can verify again in the disease brain tissue according to recent advances in neuroimaging techniques, and molecular biological research.
