Does research on schizophrenia with rare characteristic findings contribute to “understanding schizophrenia”? -Consideration from specific cases such as chromosomal translocations and side effects by medications-

Abstract

Despite advances in the treatment of schizophrenia, there are still limitations, and we have wondered if clarifying the pathophysiology of schizophrenia might help solve such problems. We are investigating the biological pathogenesis of schizophrenia by following phenomena that may be related to the pathophysiology of schizophrenia. Here, we present our attempts using chromosomal translocations and the side effects of antipsychotic drugs as clues.