Abstract
We found age dependence of amylase activity and amylase isoenzyme pattern in serum of neonate and infancy. Total serum amylase activity was measured by a chromogenic method and serum amylase isoenzyme was determined by electrophoresis on Titan III-Lipo membrane. Amylase activity in cord serum of neonate at birth was on remarkably low level, so that cord serum was concentrated with Liphogel before isoenzy meanalysis. Serum amylase activity was on low level under 4 months of age after delivery, increased with age after that and reached the normal adult level by approximately 10 years of age. A little Amylase-1 of pancreatic isoennzyme was detected in cord serum at birth and age-depenpent increase of Amylase-1 was observed in serum of neonate and infancy after delivery. Movements after delivery of pancreatic and salivary type amylase are different respectively, which show that function of external secretion in pancreas develops and that of salivary gland also develops, and we consider the movements are phenomena of physiological adaptation in growing neonate and infancy.
