Non Ehzymatic Glycosylation of Protein: Its Role in Diabetes

Abstract

Proteins can undergo a variety of post-translational modifications.One of the most widespread is non-enzymatic glycosylation. This phenomenon has gained considerable attention because of its association with diabetes mellitus and the possibility that it may contribute to the long-term complications of the disease. This concise review will focus on non-enzymatic glycosylation of hemoglobin and other proteins and the relationship between this process and diabetes.