The esterolytic activity of new arginine esterase (s), which was separated from kallikrein, was measured by using N-α-tosyl-L-arginine methyl ester (Tos-Arg-Me) as substrate in human urine. The urine of the patients with primary aldosteronism exhibited markedly raised new arginine esterases activity, although the patients with hypertension or chronic nephritis showed no significant elevation of this engyme activity.
