he C-Reactive Protein Measurement of a Dog Serum

Abstract

To determine the potential use of C-reactive protein (CRP) reagents in dogs, CRP was measured in untreated beagles from an experimental animal facility and in inflammation models. CRP in 80% of the beagles from the experimental animal facility was under 20 mg/l which is clinically said to be the highest normal range in veterinary medicine. CRP in dogs had a sensitive reaction to inflammation and tissue damage. From these results, CRP was judged to be an effective marker for diagnosis of latent infectious diseases and a good parameter for determining normal animals in commercial experimental animals. Because of its sensitive reaction to inflammation and tissue damage, CRP is also a good marker for screening toxicity in non-clinical studies.