Japanese Journal of Clinical Chemistry
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
Interference of Cyproterone-17-Acetate in urinary 17-keto steroids assay
YOSHIHISA YAMAGUCHICHOZO HAYASHI
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1978 Volume 7 Issue 2 Pages 192-193

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Abstract
Interference of Cyproterone Acetate which is an alkyl substituted steroid used as a drug for anti-androgen was observed on urinary 17-ketosteroids assay. This drug used for patients, sometimes for child, with abnormal high androgen activity is metabolized to 17-keto derivatives and interfer on the 17-ketosteroids assay. Color by Zimmermann reaction from patients urine was orange-brown. and it is impossible to correct the value so that it is prefered to stop the administration of the drug before the test.
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