Abstract
In Mekong river basin, population increase and economic growth may cause the water pollution problem in the future. This study aimed to assess spatial water quality environment in main stream and tributaries of Mekong river. For that purpose, liner regression model to estimate unit of nutrient pollution loading and water circulation model to estimate river discharge were developed, and then river nutrient concentration was also calculated. As a result, estimated unit of nutrient pollution loading expressed the characteristics of wastewater treatment process and agricultural level in Mekong river basin. Calculated river discharge and annual average river nutrient concentration were good agreement with observed data.