An autopsy case of intestinal Behçet’s disease with sacroiliitis accompanied by myelodysplastic syndrome with trisomy 8

Abstract

  Here we described an autopsy case of intestinal Behçet’s disease with sacroiliitis associated with myelodysplastic syndrome (RAEB-t, 8+). Over twenty cases of Behçet’s disease associated with myelodysplastic syndrome have been reported in preliterature so far. The majority of them are incomplete type of Behçet’s disease having intestinal ulceration. Of those, trisomy 8 is the most common chromosomal abnormality. We reviewed similar cases reported and investigated the association of intestinal Behçet’s disease with trisomy 8. The association of sacroiliitis with Behçet’s disease is also studied.