Abstract
In this report we describe the effects of IFN-γ on IL 2 receptor (IL 2 R) expression in peripheral blood monocytes from childhood acute leukemia patients.
1: IFN-γ had an enhancing effect on IL 2 R on monocytes.
2: IL 2 R expression on monocytes incubated in medium alone was more pronounced for patients, but on monocytes incubated in medium with IFN-γ was more pronounced for healthy adults.
3: The enhancing effect of IFN-γ on IL 2 R expression was reduced by more than 1×10-8mol/L 6-MP but MTX or 6-MP itself does not have any effects on IL 2 R expression.
