A case of antiphospholipid antibody syndrome associated with Evans' syndrome and chronic thyroiditis

Abstract

A 33-year-old woman who was diagnosed as having Evans' syndrome 5 years before admission was transferred to our hospital because of dysarthria. On admission, MRI of the brain revealed multiple infarction. Laboratory examination showed anemia with positive Coombs test, thrombocytopenia with platelet associated IgG, elongation of APTT, biological false positive for syphilis, positive test for anti-microsome or thyroglobulin hemagglutination test, and anti-cardiolipin antibody. These findings suggest that she had antiphospholipid antibody syndrome, Evans' syndrome, and chronic thyroiditis. Anti-cardiolipin antibody might be crossreactive with platelets, red cells, and thyroid tissue.