Japanese Journal of Clinical Immunology
Online ISSN : 1349-7413
Print ISSN : 0911-4300
ISSN-L : 0911-4300
A case of eosinophilic fasciitis with eosinophil infiltration in the lungs
Yasushi KamiyaKimimasa NakabayashiYoshihiro ArimuraMichihiko SuzukiShinobu MinoshimaToshihiko Nagasawa
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1994 Volume 17 Issue 1 Pages 66-71

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Abstract
We described a patient of eosinophilic fasciitis with eosinophil infiltration in the lungs. The patient was a 23 years old female who developed bilateral swollen and painful legs, and peripheral blood eosinophilia after the episode of upper respiratory infection. A wedge biopsy of the leg revealed thickned fascia and remarkable eosinophil infiltration in the perimyosium. Transbronchial lung biopsy showed significant infiltration of eosinophils in the alveoli and alveolar walls, although the chest X-ray showed only slight infiltrationshadows and pulmonary function test were within normal limits. This case was diagnosed to have eosinophilic fasciitis by the findings of bilateral swollen and painful legs, and peripheral blood eosinophilia, and the characteristic biopsy findings of the fascia. Until now eosinophilic fasciitis associated with lung involvement has not been reported. Thus, this case was of note to study a new spectrum of eosinophilic fasciitis.
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© The Japan Society for Clinical Immunology
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