2020 Volume 3 Issue 2 Pages 342-348
We report the case of 52-year-old Japanese female who was diagnosed with allergic contact dermatitis（ACD due to the temple tips of her plastic spectacle frames. The patient developed scaly infiltrative erythema on the upper parts of the bilateral pinnae after wearing the spectacles for 6 months. Patch tests produced positive results for scrapings from the temple tips but negative results for oil-soluble dyes such as C.I. Solvent Orange 60. When the temple tips were removed from the frames, their metal cores were found to be corroded. Fluorescent X-ray spectroscopy-based metal component analysis revealed that nickel was present in the temple tip resin and was one of the main components of the corroded metal cores. A patch test with nickel sulfate produced strong positive results. Some ultraviolet absorbers and plasticizers, which were detected by gas chromatography/mass spectrometry-based analysis, produced negative patch test results. We finally diagnosed the patient with nickel allergy after being sensitized to nickel, which had permeated through the metal cores of the spectacle frames after they had been corroded by sweat and sebum.
（日本皮膚免疫アレルギー学会雑誌, 3（2）：342-348, 2020）
