Abstract

Since June 2023, I have been engaged in research at the Meakins-Christie Laboratories, located within the McGill University Health Centre in Montreal, Canada, under the supervision of Professor Martin. My work has focused on investigating immune responses using a murine model of irritant-induced asthma. In this study, we elucidated IL-33-induced polarization of pulmonary macrophages and reported the involvement of M2 macrophages in addition to the IL-33/ILC2 axis. We are also currently analyzing the adaptive mechanisms of immune responses following repeated exposure to chlorine gas. Furthermore, I have been involved in clinical research examining sputum cellularity and immune biomarkers during acute exacerbations of asthma. I am deeply grateful for these valuable experiences and the generous support I have received.