Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
Online ISSN : 1882-8272
Print ISSN : 0388-1601
ISSN-L : 0388-1601
The Effect of Amrinone on Left Ventricular Regional Wall Motion in Patients with Myocardial Infarction
Hajime KIRIGAYATomohiro IIIZUMIShingi ABEAkihiko NOGAMIKoichi TANIGUCHI
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JOURNAL FREE ACCESS

1990 Volume 21 Issue 2 Pages 449-452

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Abstract
To investigate the effect of Amrinone (AMR) on left ventricular regional wall motion, we performed contrast ventriculography before and after administration of AMR in patients with myocardial infarction. Three patients had anterior myocardial infarction, one had inferior infarction, and one had posterior infarction. All patients had abnormal regional wall motions corresponding with the territory of electrocardiographic abnormal ities. In four of the five patients the regional wall motions of the infarct area were improved by administration of AMR (1mg/kg). The results suggest that the positive inotropic effect of AMR may influence not only normal myocardium but also stunned myocardium.
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© The Japanese Society of Clinical Pharmacology and Therapeutics
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