Abstract
The hypotensive effect of Pyratrione [3- (3-hydroxy-hydrocinamoyl) -b-me-thyl-2H-pyran-2, 4 (3H) -dione] has been demonstrated in spontaneously hyper-tensive rabbits. This study was undertaken to see whether or not this agent could significantly lower the blood pressure of chronic Goldblatt type hypertension of rabbits. The result showed that successive 3 days adminitstration of this agent effectively lowered the blood pressure of these hypertensive rabbits, when com-pared with the blood pressure in pre-and post-administration phases of these animals as well as with the blood pressure of the control rabbits.
