Chemical biology of auxin signal transduction and transport(The JSCRP Award,The Society Awards Lecture)

Abstract

Indole 3-acetic acid is a major naturally occurring auxin. Molecular genetics approach using a model plant Arabidopsis have demonstrated the molecular mechanism of auxin action. However, it is still hard to study the physiological role of auxin beyond the model plants. To complement the molecular genetic approach to auxin biology, we have been investigated the chemical probes on auxin signaling and transport, such as antagonist specific for TIR1/AFB auxin receptors, caged auxins and competitive auxin transport inhibitors. Our work substantiates the useful chemical tools for plant biology.