2018 Volume 53 Issue 1 Pages 43-52
Plants are in nature challenged and colonized by a rich diversity of microbes, ranging from pathogens to mutualists. Plants have evolved an elaborate, multilayered immune system to recognize and manage these plant-infecting microbes. An important immune layer is provided by pattern recognition receptors (PRRs) that detect microbe- and host damage-associated molecular patterns (MAMPs and DAMPs, respectively) at the cell surfaces. PRRs have emerged as a promising toolset to confer durable, cost-effective and broad-spectrum disease resistance on crop plants. Here, we discuss the functional significance of PRRs in plant-microbe interactions and their exploitation to develop a more sustainable setting of agriculture.