Journal of Japanese Society for Clinical Renal Transplantation
Online ISSN : 2760-1714
Print ISSN : 2187-9907
Comparative study of renal transplantation with and without simultaneous bilateral nephrectomies and decrease of kidney volume after renal transplantation for autosomal dominant polycystic kidney disease
Akihito SannomiyaKazuhiro IwadohIchiro KoyamaIchiro NakajimaShouhei FuchinoueSyuji Sakai
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2013 Volume 1 Issue 2 Pages 166-169

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Abstract

The necessity and timing of nephrectomy are controversial when renal transplantation for patients with autosomal dominant polycystic kidney disease (ADPKD). We experienced 30 patients with ADPKD underwent renal transplantation from February 2002 to December 2011. Of the 30 patients, we divided into 10 renal transplantation with simultaneous bilateral nephrectomies, and 20 without bilateral nephrectomies. Demographic data, intraoperative data, graft survival rate, and patient survival rate were compared. There were no differences regarding demographic data. Operating time was longer (426 vs. 194.6min, p=0.000076) and blood transfusions was larger (746 vs. 115mL, p=0.0024) in bilateral nephrectomies group. There were no differences in graft and patient survival rates. Volumetry was retrospectively conducted using simple computed tomography scan before and after transplantation in 12 non-bilateral nephrectomies patients. Kidney volumes were reduced in all patients after renal transplantation. Because the volume of native polycystic kidneys could be reduced after renal transplantation, It seems that there is no necessity of bilateral native nephrectomies if there are neither a hemorrhage of the cyst, infection nor a possibility of the malignant tumor for patients with ADPKD.

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