Renal transplantation in HIV-infected CKD patients

Abstract

With the advent of highly active antiretroviral therapy (ART), the mortality in patients with human immunodeficiency virus (HIV) infection is almost same as general population. HIV associated complications and opportunistic infections have declined and end stage renal disease has increased. CKD patients who need renal replacement therapy are increasing. In some cases, HIV has been acquired after transplantation. HIV-positive recipients have superior survival when compared with HIV-infected dialysis patients. However, it should be noted percentage of rejection, drug interactions, management of hepatitis B or C, and post-transplant infectious diseases. HIV specialist, transplant surgeon and physician, nephrologist, hepatologist, pharmacist, and clinical psychologist must be cooperated. Transplant surgeon and physician should know the problems and outcomes in kidney transplant or dialysis. Isummarize the treatment strategies for HIV-positive CKD patients.