Abstract
Thermodynamic nature of bilayer assembly of phospholipids in aqueous medium have been reviewed mainly from the view point of surface properties of lipid dispersions. In particular, emphasized was usefulness of the equilibrium spreading pressure (Πe) measurement at the air-water interface related to the phase studies of lipid bilayers. The phospholipids studied were dimyristoylphosphatidylcholine (DMPC), dipalmitoylphosphatidylcholine (DPPC), and dimyristoylphosphatidylglycerol (DMPG). Also described briefly were the precise heat capacity measurements of DMPG dispersion in aqueous NaCl in the temperature range above main transition, the formation of complex between phospholipids and cholesterol, and the solubilization of apolar compounds in DMPC bilayer.