Changes in ocular blood flow measured by laser speckle flowgraphy and regional cerebral oxygen saturation during aortic arch surgery with selective cerebral perfusion

Abstract

　The present study was designed to investigate the changes in ocular blood flow measured by laser speckle flowgraphy (LSFG) and regional cerebral tissue oxygen saturation (rSO₂) during aortic arch surgery with cardiopulmonary bypass (CPB) using antegrade selective cerebral perfusion (ASCP).

　Twenty-one patients undergoing aortic arch surgery with CPB using ASCP were enrolled in this study. Ocular blood flow using LSFG and rSO₂ were measured at the following four points: (1) after the administration of anesthesia; (2) 30 minutes after the beginning of CPB; (3) 30 minutes after the beginning of ASCP; and (4) 60 minutes after cessation of CPB. Percentage change in ocular blood flow and rSO₂ at measurement points (2), (3), and (4) was calculated when the values of ocular blood flow and rSO₂ at measurement point (1) ware defined as the reference flow. Percentage change of ocular blood flow in the measurement points (2) and (3) was significantly reduced compared with the baseline value of the measurement point (1). On the other hand, percentage change of rSO₂ at measurement point (2) was significantly increased compared with the baseline value of the measurement point (1). Measurement of ocular blood flow by LSFG with combination of rSO₂ monitor might be feasible for optimal cerebral monitor during aortic arch surgery with SCP.