Efficacy of concurrent hemodiafiltration during cardiovascular surgery using cardiopulmonary bypass

Abstract

【Aim】

　In cardiovascular surgery cases using cardiopulmonary bypass (CPB), severe inflammation is generated as an effect of the disease itself, as well as a reaction to the presence of a foreign-body during CPB, which creates tissue damage that may also lead to multiple-organ failure. To counter this, we implemented and examined the effects of continuous hemodiafiltration (HDF) during surgery with the aim of inhibiting inflammation.

【Method】

　We retrospectively compared a concurrent HDF group to a non-HDF group.

【Results】

　In the concurrent HDF group, cardiac, pulmonary, and renal functions were all well-maintained. Electrolyte management during CBP was also simple.

【Conclusion】

　These results suggest that concurrent HDF mitigates the effect of the underlying disease, as well as the reaction to a biologically invasive surgical procedure and CPB. It may also lead to a good postoperative course.