A case of anticoagulation management using heparin-activated clotting time titration curve and Sonoclot^® in an antiphospholipid syndrome patient undergoing cardiac valvular surgery

Abstract

　Perioperative management of antiphospholipid syndrome (APS) in patients undergoing cardiac surgery is challenging as an anticoagulation strategy for cardiac surgery with cardiopulmonary bypass (CPB) has not been established. Reports of difficulty in managing perioperative APS are increasing, and coagulation analyzers may help in the management of APS during cardiac surgery involving CPB. Here, we report a case of anticoagulation management using a heparin-activated clotting time (heparin-ACT) titration curve and Sonoclot^® in a patient with APS undergoing cardiac valvular surgery.