Abstract
Intradialysis hypotension is encountered more frequently in diabetic patients than in nondiabetic patients. In this study, we evaluated the plasma refilling rate (PRR) and circulating blood volume change (ΔBV) during hemodialysis using CRIT-LINE™ (In-Line Diagnostics, UT, USA) in ten diabetic and ten nondiabetic hemodialysis patients. As a result, there were no significant differences in the averaged value of PRR between diabetic and nondiabetic patients. There was a correlation between ΔBV and PRR in nondiabetic patients (r=-0.64), but not in diabetic patients. At high ΔBV levels (less than 9%), PRR was significantly lower (0.71±0.10 vs. 0.90±0.15, p<0.01) and the rate of change in mean blood pressure tended to be lower (10.07±12.21% vs. 1.83±10.09%, p=0.11) in diabetic patients, compared with that in nondiabetic patients. In conclusion, an inadequate PRR to ΔBV observed in diabetic patients was one of the factors affecting intradialysis hypotension.
