Abstract
For end stage renal failure (ESRD) patients associated with bone marrow failure syndrome, thrombocytopenia and defective thrombocyte function can cause fatal hemorrhagic complications on initiation of dialysis therapy. In this paper, we report two elderly patients with ESRD complicated by bone marrow failure syndrome, such as myelodysplatic syndrome (MDS) or myelofibrosis (MF). These two patients have been well maintained by peritoneal dialysis (PD) for the treatment of ESRD with periodic administration of blood transfusion and erythropoietin. Prior to the PD-catheter insertion operation, platelet transfusion was performed to prevent hemorrhagic problems. After the initiation of PD therapy, there was improvement of symptoms caused by uremia and volume overload as well as anemia. Moreover, performance status and quality of life could be improved because of the diminished symptoms associated with uremia and anemia.
