Abstract
A 66-year-old male was admitted to our hospital for surgical resection of renal cell carcinoma associated with the dialysis kidney. He had been diagnosed with congenital antithrombin III (AT III) deficiency 27 years previously when he had unsuccessful kidney transplantation. Before the present surgery, AT III products were administered at an appropriate dosage in order to maintain AT III activity above 100%. Laparoscopic nephrectomy was performed successfully, and the patient had no surgical complications including thrombosis although continued administration of AT III products was required for a few days postoperatively. We concluded that the most important issue for operating on patients with AT III deficiency, even if they are on maintenance hemodialysis, is to administer an appropriate dosage of AT III products and to maintain AT III activity at an appropriate level.
