Abstract
International Kidney Evaluation Association Japan (IKEAJ) aims early detection and treatment of CKD. Early detection of CKD is important, but actually it's hard for us to detect earlier. Many issues are pointed out. Firstly, who to choose for examination ; to cover all Japanese it is impossible in terms of cost. Then, what examination would be appropriate? The examination should be simple and easy in order to be conducted nationwide. Furthermore, efficiency is also important. Also, global criteria should be applied for diagnostic criteria. IKEAJ developed KEEP JAPAN Program based on KEEP by US National Kidney Foundation (NKF). KEEP JAPAN is conducted for those who would pose some risks of diabetes, hypertension or have family members with the diseases including kidney disease, and provides CKD reviews CKD incidence and risk factors in our country. CKD incidence (stage 1-4) is 26.7% by albumin and creatinine ratio and eGFR. CKD incidence among participants with diabetes is 35.0%, which is 1.7 time higher than non-diabetes participants. CKD incidence among hypertension participants is 34.8%, which is 3.4 times higher than non-hypertension participants. Prevalence of CVD among participants with CKD is 28.9%, which is 1.9 time higher than non-CKD participants. Also, prevalence of CVD among of participants with history of diabetes and hypertension is 38.3%. CKD incidence is higher than we expected. KEEP JAPAN identifies high-risk population with CKD based on the definition of this program, and compares the figures with the data from other countries. WHO places NCD management as one of the strategies and focuses on CVD, cancer, diabetes and chronic respiratory disease. It is evident that these diseases are closely related to risks from negative lifestyle habits such as smoking, unhealthy diet, lack of exercise, and alcohol. Although diabetes, CVD and CKD are closely related to developing complication, CKD itself is not so recognized in the society as the above mentioned life-style related diseases. I would say that CKD is the new major disease in Japan. Raising awareness of CKD globally can be a CKD management.