Abstract
A 45-year-old female with a history of chronic renal disease attended our hospital in 2008 with acute intermittent porphyria (AIP). The following year, her renal function deteriorated, and her general condition, and clinical and laboratory findings fulfilled the Japanese criteria for hemodialysis. The porphyrias are metabolic disorders of heme biosynthesis that are triggered and worsened by a number of different drugs. Hemodialysis was initiated in 2009, and we prescribed amlodipine besylate and epoetin beta, paying particular attention to drug safety. Currently, the patient is on hemodialysis and is still taking the medications mentioned above, without any exacerbation of porphyria.
